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EC 1.10.3.4 Details
EC number
1.10.3.4
Accepted name
o-aminophenol oxidase
Reaction
4 2-aminophenol + 3 O2 = 2 2-aminophenoxazin-3-one + 6 H2O
Other name(s)
isophenoxazine synthase, o-aminophenol:O2 oxidoreductase, 2-aminophenol:O2 oxidoreductase
Systematic name
2-aminophenol:oxygen oxidoreductase
CAS registry number
9013-85-8
Comment
A flavoprotein which catalyses a 6-electron oxidation. The enzyme from the plant Tecoma stans requires Mn2+ and FAD [1] whereas the fungus Pycnoporus coccineus requires Mn2+ and riboflavin 5′-phosphate [2], the bacteria Streptomyces antibioticus requires Cu2+ [4] and the plant Bauhenia monandra does not require any co-factors [3].
History
created 1972, modified 2006
EC Tree
1.6.4.1 created 1961, deleted 2002
1.6.4.2 created 1961, modified 1989, deleted 2002
1.6.4.3 created 1961, modified 1976, deleted 1983
1.6.4.4 created 1965, deleted 2002
1.6.4.5 created 1972, deleted 2002
1.6.4.6 created 1972, deleted 2002
1.6.4.7 created 1978, deleted 2002
1.6.4.8 created 1989, deleted 2002
1.6.4.9 created 1992, deleted 2002
1.6.4.10 created 1992, deleted 2002
1.11.1.4 created 1961, deleted 1964, reinstated 1965 as EC 1.13.1.12, deleted 1972