Any feedback?
Please rate this page
(ecexplorer.php)
(0/150)

BRENDA support

EC Explorer

EC 2.5.1.94 Details
EC number
2.5.1.94
Accepted name
adenosyl-chloride synthase
Reaction
S-adenosyl-L-methionine + chloride = 5-deoxy-5-chloroadenosine + L-methionine
Other name(s)
chlorinase, 5′-chloro-5′-deoxyadenosine synthase
Systematic name
S-adenosyl-L-methionine:chloride adenosyltransferase
Comment
This enzyme, isolated from the marine bacterium Salinispora tropica, catalyses an early step in the pathway leading to biosynthesis of the proteosome inhibitor salinosporamide A. The enzyme is very similar to EC 2.5.1.63, adenosyl-fluoride synthase, but does not accept fluoride.
History
created 2011
EC Tree
1.11.1.4 created 1961, deleted 1964, reinstated 1965 as EC 1.13.1.12, deleted 1972