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EC 3.5.99.11 Details
show Brenda entryEC number
3.5.99.11
Accepted name
2-aminomuconate deaminase (2-hydroxymuconate-forming)
Reaction
2-aminomuconate + H2O = (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + NH3
Other name(s)
cnbZ (gene name)
Systematic name
2-aminomuconate aminohydrolase [(2Z,4E)-2-hydroxyhexa-2,4-dienedioate-forming]
Comment
The enzyme, characterized from the bacterium Comamonas testosteroni CNB-1, converts 2-aminomuconate to 2-hydroxyhexa-2,4-dienedioate, unlike the enzymes from Pseudomonas, which produce (3E)-2-oxohex-3-enedioate (see EC 3.5.99.5, 2-aminomuconate deaminase). The enzyme also acts on 2-amino-5-chloromuconate.
History
created 2016 as EC 3.5.1.120, transferred 2017 to EC 3.5.99.11
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.6.2.1 created 1961, deleted 1965 1.6.2.3 created 1972, deleted 1965 1.13.11.21 created 1972, deleted 2001
