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EC 2.1.1.345 Details
EC number
2.1.1.345
Accepted name
psilocybin synthase
Reaction
2 S-adenosyl-L-methionine + 4-hydroxytryptamine 4-phosphate = 2 S-adenosyl-L-homocysteine + psilocybin (overall reaction);;(1a) S-adenosyl-L-methionine + 4-hydroxytryptamine 4-phosphate = S-adenosyl-L-homocysteine + 4-hydroxy-N-methyltryptamine 4-phosphate;;(1b) S-adenosyl-L-methionine + 4-hydroxy-N-methyltryptamine 4-phosphate = S-adenosyl-L-homocysteine + psilocybin
Other name(s)
PsiM
Systematic name
S-adenosyl-L-methionine:4-hydroxytryptamine-4-phosphate N,N-dimethyltransferase
Comment
Isolated from the fungus Psilocybe cubensis. The product, psilocybin, is a psychoactive compound.
History
created 2017
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