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EC 1.2.1.60 Details

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EC number

1.2.1.60

Accepted name

5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase

Reaction

5-carboxymethyl-2-hydroxymuconate semialdehyde + H₂O + NAD⁺ = 5-carboxymethyl-2-hydroxymuconate + NADH + 2 H⁺

Other name(s)

carboxymethylhydroxymuconic semialdehyde dehydrogenase

Systematic name

5-carboxymethyl-2-hydroxymuconic-semialdehyde:NAD⁺ oxidoreductase

CAS registry number

63241-20-3

Comment

Involved in the tyrosine degradation pathway in Arthrobacter sp.

History

created 2000

EC Tree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.2 Acting on the aldehyde or oxo group of donors

1.2.1 With NAD⁺ or NADP⁺ as acceptor

1.2.2 With a cytochrome as acceptor

1.2.2.1 formate dehydrogenase (cytochrome)

1.2.2.2 pyruvate dehydrogenase (cytochrome)

1.2.2.3 formate dehydrogenase (cytochrome-c-553)

1.2.2.4 carbon-monoxide dehydrogenase (cytochrome b-561)

1.2.3 With oxygen as acceptor

1.2.4 With a disulfide as acceptor

1.2.5 With a quinone or similar compound as acceptor

1.2.7 With an iron-sulfur protein as acceptor

1.2.98 With other, known, physiological acceptors

1.2.99 With unknown physiological acceptors

1.3 Acting on the CH-CH group of donors

1.4 Acting on the CH-NH₂ group of donors

1.5 Acting on the CH-NH group of donors

1.6 Acting on NADH or NADPH

1.7 Acting on other nitrogenous compounds as donors

1.8 Acting on a sulfur group of donors

1.9 Acting on a heme group of donors

1.10 Acting on diphenols and related substances as donors

1.11 Acting on a peroxide as acceptor

1.12 Acting on hydrogen as donor

1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.15 Acting on superoxide as acceptor

1.16 Oxidizing metal ions

1.17 Acting on CH or CH₂ groups

1.18 Acting on iron-sulfur proteins as donors

1.19 Acting on reduced flavodoxin as donor

1.20 Acting on phosphorus or arsenic in donors

1.21 Catalysing the reaction X-H + Y-H = X-Y

1.21.1 With NAD⁺ or NADP⁺ as acceptor

1.21.3 With oxygen as acceptor

1.21.4 With a disulfide as acceptor

1.21.98 With other, known, physiological acceptors

1.21.99 With unknown physiological acceptors

1.22 Acting on halogen in donors

1.23 Reducing C-O-C group as acceptor

1.23.1 With NADH or NADPH as donor

1.23.5 With a quinone or similar compound as acceptor

1.97 Other oxidoreductases

1.98 Enzymes using H₂ as reductant (deleted subclass)

1.98.1. undefined

1.99 Other enzymes using O₂ as oxidant (deleted subclass)