Any feedback?
Please rate this page
(ecexplorer.php)
(0/150)

BRENDA support

EC Explorer

EC 5.3.1.27 Details
EC number
5.3.1.27
Accepted name
6-phospho-3-hexuloisomerase
Reaction
D-arabino-hex-3-ulose 6-phosphate = D-fructose 6-phosphate
Other name(s)
3-hexulose-6-phosphate isomerase, phospho-3-hexuloisomerase, PHI, 6-phospho-3-hexulose isomerase, YckF
Systematic name
D-arabino-hex-3-ulose-6-phosphate isomerase
Comment
This enzyme, along with EC 4.1.2.43, 3-hexulose-6-phosphate synthase, plays a key role in the ribulose-monophosphate cycle of formaldehyde fixation, which is present in many microorganisms that are capable of utilizing C1-compounds [1]. The hyperthermophilic and anaerobic archaeon Pyrococcus horikoshii OT3 constitutively produces a bifunctional enzyme that sequentially catalyses the reactions of EC 4.1.2.43 (3-hexulose-6-phosphate synthase) and this enzyme [4].
History
created 2008
EC Tree
1.2.1.1 created 1961, modified 1982, modified 2002, deleted 2005
1.2.1.6 created 1961, deleted 1965
1.2.1.14 created 1961, deleted 1984
1.2.1.34 created 1972, deleted 1983 [transferred to EC 1.1.1.180, deleted 1984]
1.2.1.35 created 1972, deleted 1984
1.2.1.37 created 1972, deleted 1984
1.2.1.55 created 1990, deleted 2003
1.2.1.56 created 1990, deleted 2003