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EC 1.5.99.12 Details
EC number
1.5.99.12
Accepted name
cytokinin dehydrogenase
Reaction
N6-prenyladenine + acceptor + H2O = adenine + 3-methylbut-2-enal + reduced acceptor
Other name(s)
N6-dimethylallyladenine:(acceptor) oxidoreductase, 6-N-dimethylallyladenine:acceptor oxidoreductase, OsCKX2, CKX, cytokinin oxidase/dehydrogenase, N6-dimethylallyladenine:acceptor oxidoreductase
Systematic name
N6-prenyladenine:acceptor oxidoreductase
CAS registry number
55326-39-1
Comment
A flavoprotein (FAD). Catalyses the oxidation of cytokinins, a family of N6-substituted adenine derivatives that are plant hormones, where the substituent is a prenyl group. Although this activity was previously thought to be catalysed by a hydrogen-peroxide-forming oxidase, this enzyme does not require oxygen for activity and does not form hydrogen peroxide. 2,6-Dichloroindophenol, methylene blue, nitroblue tetrazolium, phenazine methosulfate and copper(II) in the presence of imidazole can act as acceptors. This enzyme plays a part in regulating rice-grain production, with lower levels of the enzyme resulting in enhanced grain production [2].
History
created 2001
EC Tree
1.6.99.2 created 1961 as EC 1.6.5.2, transferred 1965 to EC 1.6.99.2, deleted 2005
1.6.99.4 created 1965, deleted 1972
1.6.99.7 created 1972, modified 1981 (EC 1.6.99.10 created 1978, incorporated 1981), deleted 2003
1.6.99.8 created 1972, deleted 2002
1.6.99.9 created 1972, deleted 2002
1.6.99.10 created 1978, deleted 1981
1.6.99.11 created 1989, deleted 2002
1.6.99.12 created 1989, deleted 2002
1.6.99.13 created 1992, deleted 2002