EC Explorer

7.4.2.11

ABC-type methionine transporter

(1) ATP + H₂O + L-methionine-[methionine-binding protein]_{[side 1]} = ADP + phosphate + L-methionine_{[side 2]} + [methionine-binding protein]_{[side 1]} ;;(2) ATP + H₂O + D-methionine-[methionine-binding protein]_{[side 1]} = ADP + phosphate + D-methionine_{[side 2]} + [methionine-binding protein]_{[side 1]}

methionine transporting ATPase, methionine ABC transporter, metNIQ (gene names)

ATP phosphohydrolase (ABC-type, methionine-importing)

ABC-type (ATP-binding cassette-type) transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. A bacterial enzyme that interacts with an extracytoplasmic substrate binding protein and functions to import methionine. The enzyme from Escherichia coli K-12 mediates the high affinity transport of both L- and D-methionine, as well as methionine-S-oxide and N-acetyl-DL-methionine.

created 2019