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EC 1.14.14.90 Details
EC number
1.14.14.90
Accepted name
isoflavone 2′-hydroxylase
Reaction
an isoflavone + [reduced NADPH—hemoprotein reductase] + O2 = a 2′-hydroxyisoflavone + [oxidized NADPH—hemoprotein reductase] + H2O
Other name(s)
isoflavone 2′-monooxygenase, CYP81E1, CYP Ge-3
Systematic name
isoflavone,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (2′-hydroxylating)
CAS registry number
110183-49-8
Comment
A cytochrome P-450 (heme-thiolate) protein. Acts on daidzein, formononetin and genistein. EC 1.14.14.89, 4′-methoxyisoflavone 2′-hydroxylase, has the same reaction but is more specific as it requires a 4′-methoxyisoflavone.
History
created 2005 as EC 1.14.13.89, transferred 2018 to EC 1.14.14.90
EC Tree
1.14.14.2 created 1972, deleted 1976
1.14.14.4 created 2000, deleted 2002