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EC 5.5.1.32 Details
EC number
5.5.1.32
Accepted name
12-epi-hapalindole U synthase
Reaction
3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole = 12-epi-hapalindole U
Other name(s)
famC1 (gene name), HpiC1 (gene name)
Systematic name
3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole cyclase (12-epi-hapalindole U-forming)
Comment
The enzyme, characterized from the cyanobacterium Fischerella ambigua UTEX 1903, forms the core structure of the 12-epi-hapalindole family of alkaloids.
History
created 2018
EC Tree
1.14.14.2 created 1972, deleted 1976
1.14.14.4 created 2000, deleted 2002