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EC 1.14.14.142 Details
EC number
1.14.14.142
Accepted name
8-dimethylallylnaringenin 2′-hydroxylase
Reaction
sophoraflavanone B + [reduced NADPH—hemoprotein reductase] + O2 = leachianone G + [oxidized NADPH—hemoprotein reductase] + H2O
Other name(s)
8-DMAN 2′-hydroxylase
Systematic name
sophoraflavanone-B,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (2′-hydroxylating)
Comment
A membrane-bound cytochrome P-450 (heme-thiolate) protein that is associated with the endoplasmic reticulum [1,2]. This enzyme is specific for sophoraflavanone B as substrate. Along with EC 2.5.1.70 (naringenin 8-dimethylallyltransferase) and EC 2.5.1.71 (leachianone G 2′′-dimethylallyltransferase), this enzyme forms part of the sophoraflavanone G biosynthetic pathway.
History
created 2007 asEC 1.14.13.103, transferred 2018 to EC 1.14.14.142
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