EC Explorer

7.4.2.5

bacterial ABC-type protein transporter

ATP + H₂O + protein_{[side 1]} = ADP + phosphate + protein_{[side 2]}

PrtDEF (gene names), hasDEF (gene names), peptide-transporting ATPase (ambiguous)

ATP phosphohydrolase (ABC-type, peptide-exporting)

An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. This entry stands for a family of bacterial enzymes that are dedicated to the secretion of one or several closely related proteins belonging to the toxin, protease and lipase families. Examples from Gram-negative bacteria include α-hemolysin, cyclolysin, colicin V and siderophores, while examples from Gram-positive bacteria include bacteriocin, subtilin, competence factor and pediocin.

created 2000 as EC 3.6.3.43, transferred 2018 to EC 7.4.2.5, modified 2019