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EC 1.1.1.406 Details
show Brenda entryEC number
1.1.1.406
Accepted name
galactitol 2-dehydrogenase (L-tagatose-forming)
Reaction
galactitol + NAD+ = L-tagatose + NADH + H+
Other name(s)
GatDH
Systematic name
galactitol:NAD+ 2-oxidoreductase (L-tagatose-forming)
Comment
The enzyme, characterized in the bacterium Rhodobacter sphaeroides, has a wide subtrate specificity. In addition to galactitol, it primarily oxidizes D-threitol and xylitol, and in addition to L-tagatose, it primarily reduces L-erythrulose, D-ribulose and L-glyceraldehyde. It is specific for NAD+. The enzyme also shows activity with D-tagatose (cf. EC 1.1.1.16, galactitol 2-dehydrogenase).
History
created 2017
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.14.14.2 created 1972, deleted 1976 1.14.14.4 created 2000, deleted 2002
