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EC 3.5.4.43 Details
show Brenda entryEC number
3.5.4.43
Accepted name
hydroxydechloroatrazine ethylaminohydrolase
Reaction
hydroxyatrazine + H2O = N-isopropylammelide + ethylamine
Other name(s)
atzB (gene name),
2,4-dihydroxy-6-(isopropylamino)-1,3,5-triazine ethylaminohydrolase
Systematic name
hydroxyatrazine ethylaminohydrolase
Comment
Contains Zn2+. This bacterial enzyme is involved in degradation of the herbicide atrazine. The enzyme has a broad substrate range, and requires a monohydroxylated s-triazine ring with a minimum of one primary or secondary amine substituent and either a chloride or amine leaving group. It catalyses both deamination and dechlorination reactions.
History
created 2000 as EC 3.5.99.3, transferred 2016 to EC 3.5.4.43
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.14.14.2 created 1972, deleted 1976 1.14.14.4 created 2000, deleted 2002
