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EC 5.5.1.22 Details
EC number
5.5.1.22
Accepted name
(–)-bornyl diphosphate synthase
Reaction
geranyl diphosphate = (–)-bornyl diphosphate
Other name(s)
bornyl pyrophosphate synthase (ambiguous), bornyl pyrophosphate synthetase (ambiguous), (–)-bornyl pyrophosphate cyclase, bornyl diphosphate synthase, geranyl-diphosphate cyclase (ambiguous), (–)-bornyl-diphosphate lyase (decyclizing)
Systematic name
(–)-bornyl-diphosphate lyase (ring-opening)
CAS registry number
110639-17-3
Comment
Requires Mg2+. The enzyme from Tanacetum vulgare (tansy) can also use (3S)-linalyl diphosphate or more slowly neryl diphosphate in vitro. The reaction proceeds via isomeration of geranyl diphosphate to (3S)-linalyl diphosphate [3]. The oxygen and phosphorus originally linked to C-1 of geranyl diphosphate end up linked to C-2 of (–)-bornyl diphosphate [4]. cf. EC 5.5.1.8 (+)-bornyl diphosphate synthase.
History
created 2012
EC Tree
1.14.14.2 created 1972, deleted 1976
1.14.14.4 created 2000, deleted 2002