Any feedback?
Please rate this page
(ecexplorer.php)
(0/150)

BRENDA support

EC Explorer

EC 5.4.3.11 Details
EC number
5.4.3.11
Accepted name
phenylalanine aminomutase (D-β-phenylalanine forming)
Reaction
L-phenylalanine = D-β-phenylalanine
Other name(s)
admH (gene name), L-phenylalanine 2,3-aminomutase [(S)-3-amino-3-phenylpropanoate]
Systematic name
L-phenylalanine 2,3-aminomutase [(S)-3-amino-3-phenylpropanoate-forming]
Comment
The enzyme from the bacterium Pantoea agglomerans produces D-β-phenylalanine, an intermediate in the biosynthesis of the polyketide non-ribosomal antibiotic andrimid. The enzyme contains the cofactor 3,5-dihydro-5-methylidene-4H-imidazol-4-one (MIO), which is formed autocatalytically by cyclization and dehydration of the three amino-acid residues alanine, serine and glycine. cf. EC 5.4.3.10, phenylalanine aminomutase (L-β-phenylalanine forming).
History
created 2013
EC Tree
1.14.13.45 created 1992, deleted 2003