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EC 1.14.13.78 Details
EC number
1.14.13.78
Accepted name
ent-kaurene oxidase
Reaction
ent-kaur-16-ene + 3 NADPH + 3 H+ + 3 O2 = ent-kaur-16-en-19-oate + 3 NADP+ + 4 H2O (overall reaction);;(1a) ent-kaur-16-ene + NADPH + H+ + O2 = ent-kaur-16-en-19-ol + NADP+ + H2O;;(1b) ent-kaur-16-en-19-ol + NADPH + H+ + O2 = ent-kaur-16-en-19-al + NADP+ + 2 H2O;;(1c) ent-kaur-16-en-19-al + NADPH + O2 = ent-kaur-16-en-19-oate + NADP+ + H2O
Systematic name
ent-kaur-16-ene,NADPH:oxygen oxidoreductase (hydroxylating)
CAS registry number
149565-67-3
Comment
Requires cytochrome P-450. Catalyses three sucessive oxidations of the 4-methyl group of ent-kaurene giving kaurenoic acid.
History
created 2002, deleted 2018
EC Tree
1.14.13.45 created 1992, deleted 2003