Any feedback?
Please rate this page
(ecexplorer.php)
(0/150)

BRENDA support

EC Explorer

EC 7.4.2.10 Details
EC number
7.4.2.10
Accepted name
ABC-type glutathione transporter
Reaction
ATP + H2O + glutathione-[glutathione-binding protein][side 1] = ADP + phosphate + glutathione[side 2] + [glutathione-binding protein][side 1]
Other name(s)
glutathione transporting ATPase, glutathione ABC transporter, gsiACD (gene names)
Systematic name
ATP phosphohydrolase (ABC-type,glutathione-importing)
Comment
A prokaryotic ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. The enzyme from the bacterium Escherichia coli is a heterotrimeric complex that interacts with an extracytoplasmic substrate binding protein to mediate the uptake of glutathione.
History
created 2019
EC Tree
1.14.11.5 created 1972, deleted 1976