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EC 1.5.1.31 Details
EC number
1.5.1.31
Accepted name
berberine reductase
Reaction
(R)-canadine + 2 NADP+ = berberine + 2 NADPH + H+
Other name(s)
(R)-canadine synthase
Systematic name
(R)-tetrahydroberberine:NADP+ oxidoreductase
Comment
Involved in alkaloid biosynthesis in Corydalis cava to give (R)-canadine with the opposite configuration to the precursor of berberine (see EC 1.3.3.8 tetrahydroberberine oxidase). Also acts on 7,8-dihydroberberine.
History
created 2002
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