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EC 3.1.4.16 Details
show Brenda entryEC number
3.1.4.16
Accepted name
2′,3′-cyclic-nucleotide 2′-phosphodiesterase
Reaction
nucleoside 2′,3′-cyclic phosphate + H2O = nucleoside 3′-phosphate
Other name(s)
ribonucleoside 2′,3′-cyclic phosphate diesterase,
2′,3 '-cyclic AMP phosphodiesterase,
2′,3′-cyclic nucleotidase,
cyclic 2′,3′-nucleotide 2′-phosphodiesterase,
cyclic 2′,3′-nucleotide phosphodiesterase,
2′,3′-cyclic nucleoside monophosphate phosphodiesterase,
2′,3′-cyclic AMP 2′-phosphohydrolase,
cyclic phosphodiesterase:3′-nucleotidase,
2′,3′-cyclic nucleotide phosphohydrolase,
2′:3′-cyclic phosphodiesterase,
2′:3′-cyclic nucleotide phosphodiesterase:3′-nucleotidase
Systematic name
nucleoside-2′,3′-cyclic-phosphate 3′-nucleotidohydrolase
CAS registry number
9037-18-7
Comment
Also hydrolyses 3′-nucleoside monophosphates and bis-4-nitrophenyl phosphate, but not 3′-deoxynucleotides. Similar reactions are carried out by EC 4.6.1.24 (ribonuclease T1) and EC 4.6.1.18 (pancreatic ribonuclease).
History
created 1972, modified 1976
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
3.1.5.1 dGTPase
