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EC 1.3.3.10 Details
EC number
1.3.3.10
Accepted name
tryptophan α,β-oxidase
Reaction
L-tryptophan + O2 = α,β-didehydrotryptophan + H2O2
Other name(s)
L-tryptophan 2′,3′-oxidase, L-tryptophan α,β-dehydrogenase
Systematic name
L-tryptophan:oxygen α,β-oxidoreductase
CAS registry number
156859-19-7
Comment
Requires heme. The enzyme from Chromobacterium violaceum is specific for tryptophan derivatives possessing its carboxyl group free or as an amide or ester, and an unsubstituted indole ring. Also catalyses the α,β dehydrogenation of L-tryptophan side chains in peptides. The product of the reaction can hydrolyse spontaneously to form (indol-3-yl)pyruvate.
History
created 2000 as EC 1.4.3.17, transferred 2003 to EC 1.3.3.10
EC Tree
1.3.99.9 created 1976, deleted 2002