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EC 4.1.1.101 Details
EC number
4.1.1.101
Accepted name
malolactic enzyme
Reaction
(S)-malate = (S)-lactate + CO2
Other name(s)
mleA (gene name), mleS (gene name)
Systematic name
(S)-malate carboxy-lyase
Comment
The enzyme is involved in the malolactic fermentation of wine, which results in a natural decrease in acidity and favorable changes in wine flavors. It has been purified from several lactic acid bacteria, including Leuconostoc mesenteroides [1], Lactobacillus plantarum [2], and Oenococcus oeni [3,4]. The enzyme contains a tightly bound NAD+ cofactor and requires Mn2+.
History
created 2015
EC Tree
1.3.1.23 created 1972, deleted 2005
1.3.1.50 created 1992, deleted 1999
1.3.1.55 created 1999, deleted 2004