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EC 3.5.1.117 Details
EC number
3.5.1.117
Accepted name
6-aminohexanoate-oligomer endohydrolase
Reaction
[N-(6-aminohexanoyl)]n + H2O = [N-(6-aminohexanoyl)]n-x + [N-(6-aminohexanoyl)]x
Other name(s)
endo-type 6-aminohexanoate oligomer hydrolase,
Ahx endo-type-oligomer hydrolase,
6-aminohexanoate oligomer hydrolase,
Ahx-oligomer hydrolase,
nylon hydrolase,
nylon-oligomer hydrolase,
NylC,
nylon-6 hydrolase (ambiguous)
Systematic name
6-aminohexanoate oligomer endoamidohydrolase
Comment
The enzyme is involved in degradation of nylon-6 oligomers. It degrades linear or cyclic oligomers of poly(6-aminohexanoate) with a degree of polymerization greater than three (n > 3) by endo-type cleavage, to oligomers of a length of two or more (2 ≤ x < n). It shows negligible activity with N-(6-aminohexanoyl)-6-aminohexanoate (cf. EC 3.5.1.46, 6-aminohexanoate-oligomer exo hydrolase) or with 1,8-diazacyclotetradecane-2,9-dione (cf. EC 3.5.2.12, 6-aminohexanoate-cyclic-dimer hydrolase).
History
created 2014
EC Tree
1.3.1.23 created 1972, deleted 2005
1.3.1.50 created 1992, deleted 1999
1.3.1.55 created 1999, deleted 2004