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EC 1.3.1.54 Details
EC number
1.3.1.54
Accepted name
precorrin-6A reductase
Reaction
precorrin-6B + NADP+ = precorrin-6A + NADPH + H+
Other name(s)
precorrin-6X reductase, precorrin-6Y:NADP+ oxidoreductase, CobK
Systematic name
precorrin-6B:NADP+ oxidoreductase
CAS registry number
137573-72-9
Comment
The enzyme, which participates in the aerobic (late cobalt insertion) pathway of adenosylcobalamin biosynthesis, catalyses the reduction of the double bond between C-18 and C-19 of precorrin-6A. See EC 1.3.1.106, cobalt-precorrin-6A reductase, for the corresponding enzyme that participates in the anaerobic cobalamin biosynthesis pathway.
History
created 1999, modified 2004
EC Tree
1.3.1.23 created 1972, deleted 2005
1.3.1.50 created 1992, deleted 1999
1.3.1.55 created 1999, deleted 2004