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EC 6.3.2.31 Details
EC number
6.3.2.31
Accepted name
coenzyme F420-0:L-glutamate ligase
Reaction
GTP + coenzyme F420-0 + L-glutamate = GDP + phosphate + coenzyme F420-1
Other name(s)
CofE-AF,
MJ0768,
CofE
Systematic name
L-glutamate:coenzyme F420-0 ligase (GDP-forming)
Comment
This protein catalyses the successive addition of two glutamate residues to cofactor F420 by two distinct and independent reactions. In the reaction described here the enzyme attaches a glutamate via its α-amine group to F420-0. In the second reaction (EC 6.3.2.34, coenzyme F420-1—γ-L-glutamate ligase) it catalyses the addition of a second L-glutamate residue to the γ-carboxyl of the first glutamate.
History
created 2010
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