Any feedback?
Please rate this page
(ecexplorer.php)
(0/150)

BRENDA support

EC Explorer

EC 3.6.1.45 Details
EC number
3.6.1.45
Accepted name
UDP-sugar diphosphatase
Reaction
UDP-sugar + H2O = UMP + α-D-aldose 1-phosphate
Other name(s)
nucleosidediphosphate-sugar pyrophosphatase, nucleosidediphosphate-sugar diphosphatase, UDP-sugar hydrolase, UDP-sugar pyrophosphatase
Systematic name
UDP-sugar sugarphosphohydrolase
CAS registry number
55354-38-6
Comment
A divalent cation is required for activity. UDP-sugar is the best substrate, although other nucleoside-sugar diphosphates are used as substrates with similar Km values but much lower maximum velocities. Thus, this enzyme has a specificity distinct from that of ADP-sugar diphosphatase (EC 3.6.1.21). Some but not all enzymes of this class also appear to have 5′-nucleotidase (see EC 3.1.3.5) activity.
History
created 1999
EC Tree
3.6.3.13 created 2000, deleted 2001