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EC 4.1.1.96 Details
EC number
4.1.1.96
Accepted name
carboxynorspermidine decarboxylase
Reaction
(1) carboxynorspermidine = bis(3-aminopropyl)amine + CO2;;(2) carboxyspermidine = spermidine + CO2
Other name(s)
carboxyspermidine decarboxylase, CANSDC, VC1623 (gene name)
Systematic name
carboxynorspermidine carboxy-lyase (bis(3-aminopropyl)amine-forming)
Comment
A pyridoxal 5′-phosphate enzyme. Part of a bacterial polyamine biosynthesis pathway. The enzyme is essential for biofilm formation in the bacterium Vibrio cholerae [1]. The enzyme from Campylobacter jejuni only produces spermidine in vivo even though it shows activity with carboxynorspermidine in vitro [3].
History
created 2012
EC Tree
1.3.1.23 created 1972, deleted 2005
1.3.1.50 created 1992, deleted 1999
1.3.1.55 created 1999, deleted 2004