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EC 2.7.7.95 Details
EC number
2.7.7.95
Accepted name
mycocerosic acid adenylyltransferase
Reaction
ATP + a mycocerosate = diphosphate + a mycocerosoyl-adenylate
Other name(s)
fadD28 (gene name)
Systematic name
ATP:mycocerosate adenylyltransferase
Comment
The enzyme, found in certain mycobacteria, catalyses the activation of the methylated long-chain fatty acids, mycocerosic acids, by adenylation. The activated acids are transferred to the two hydroxyl groups of phthiocerols and phenolphthiocerols by PapA5, leading to formation of dimycocerosates (DIM) and dimycocerosyl triglycosyl phenolphthiocerol (PGL), respectively.
History
created 2016, deleted 2017
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