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EC 1.3.3.4 Details
EC number
1.3.3.4
Accepted name
protoporphyrinogen oxidase
Reaction
protoporphyrinogen IX + 3 O2 = protoporphyrin IX + 3 H2O2
Other name(s)
protoporphyrinogen IX oxidase, protoporphyrinogenase, PPO, Protox, HemG, HemY
Systematic name
protoporphyrinogen-IX:oxygen oxidoreductase
CAS registry number
53986-32-6
Comment
This is the last common enzyme in the biosynthesis of chlorophylls and heme [8]. Two isoenzymes exist in plants: one in plastids and the other in mitochondria. This is the target enzyme of phthalimide-type and diphenylether-type herbicides [8]. The enzyme from oxygen-dependent species contains FAD [9]. Also slowly oxidizes mesoporphyrinogen IX.
History
created 1978, modified 2003
EC Tree
1.3.99.9 created 1976, deleted 2002