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EC 3.4.11.2 Details
show Brenda entryEC number
3.4.11.2
Accepted name
membrane alanyl aminopeptidase
Reaction
Release of an N-terminal amino acid, Xaa┼Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide
Other name(s)
microsomal aminopeptidase,
aminopeptidase M,
aminopeptidase N,
particle-bound aminopeptidase,
amino-oligopeptidase,
alanine aminopeptidase,
membrane aminopeptidase I,
pseudo leucine aminopeptidase,
alanyl aminopeptidase,
alanine-specific aminopeptidase,
cysteinylglycine dipeptidase,
cysteinylglycinase,
L-alanine aminopeptidase,
CD13
CAS registry number
9054-63-1
Comment
A zinc enzyme, not activated by heavy metal ions. Type example of peptidase family M1.
History
created 1961 as EC 3.4.1.2, transferred 1972 to EC 3.4.11.2 (EC 3.4.13.6 created 1961 as EC 3.4.3.5, transferred 1972 to EC 3.4.13.6, incorporated 1997)
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
3.4.11.8 created 1972, deleted 1981 3.4.11.11 created 1978, deleted 1992 3.4.11.12 created 1978, deleted 1997
