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EC 1.3.1.51 Details
show Brenda entryEC number
1.3.1.51
Accepted name
2′-hydroxydaidzein reductase
Reaction
2′-hydroxy-2,3-dihydrodaidzein + NADP+ = 2′-hydroxydaidzein + NADPH + H+
Other name(s)
NADPH:2′-hydroxydaidzein oxidoreductase,
HDR,
2′-hydroxydihydrodaidzein:NADP+ 2′-oxidoreductase
Systematic name
2′-hydroxy-2,3-dihydrodaidzein:NADP+ 2′-oxidoreductase
CAS registry number
126125-01-7
Comment
In the reverse reaction, the 2′-hydroxyisoflavone (2′-hydroxydaidzein) is reduced to an isoflavanone. Also acts on 2′-hydroxyformononetin and to a small extent on 2′-hydroxygenistein. Involved in the biosynthesis of the phytoalexin glyceollin. The isoflavones biochanin A, daidzein and genestein as well as the flavonoids apigenin, kaempferol and quercetin do not act as substrates.
History
created 1992, modified 2004
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.3.1.23 created 1972, deleted 2005 1.3.1.50 created 1992, deleted 1999 1.3.1.55 created 1999, deleted 2004
