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EC 4.1.2.42 Details
show Brenda entryEC number
4.1.2.42
Accepted name
D-threonine aldolase
Reaction
(1) D-threonine = glycine + acetaldehyde;;
(2) D-allothreonine = glycine + acetaldehyde
Other name(s)
D-TA,
DTA,
low specificity D-TA,
low specificity D-threonine aldolase
Systematic name
D-threonine acetaldehyde-lyase (glycine-forming)
Comment
A pyridoxal-phosphate protein that is activated by divalent metal cations (e.g. Co2+, Ni2+, Mn2+ or Mg2+) [1,2]. The reaction is reversible, which can lead to the interconversion of D-threonine and D-allothreonine [1]. Several other D-β-hydroxy-α-amino acids, such as D-β-phenylserine, D-β-hydroxy-α-aminovaleric acid and D-β-3,4-dihydroxyphenylserine, can also act as substrate [1].
History
created 2007
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.14.13.45 created 1992, deleted 2003 1.14.17.2 created 1972, deleted 1984
