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EC 1.14.13.38 Details
EC number
1.14.13.38
Accepted name
anhydrotetracycline 6-monooxygenase
Reaction
anhydrotetracycline + NADPH + H+ + O2 = 12-dehydrotetracycline + NADP+ + H2O
Other name(s)
ATC oxygenase, anhydrotetracycline oxygenase, oxyS (gene name), anhydrotetracycline monooxygenase
Systematic name
anhydrotetracycline,NADPH:oxygen oxidoreductase (6-hydroxylating)
CAS registry number
70766-62-0
Comment
The enzyme, characterized from the bacterium Streptomyces rimosus, participates in the biosynthesis of tetracycline antibiotics. It can also catalyse EC 1.14.13.234, 12-dehydrotetracycline 5-monooxygenase.
History
created 1990, modified 2016
EC Tree
1.14.13.45 created 1992, deleted 2003
1.14.17.2 created 1972, deleted 1984