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EC 4.2.1.144 Details
EC number
4.2.1.144
Accepted name
3-amino-5-hydroxybenzoate synthase
Reaction
5-amino-5-deoxy-3-dehydroshikimate = 3-amino-5-hydroxybenzoate + H2O
Other name(s)
AHBA synthase,
rifK (gene name)
Systematic name
5-amino-5-deoxy-3-dehydroshikimate hydro-lyase (3-amino-5-hydroxybenzoate-forming)
Comment
A pyridoxal 5′-phosphate enzyme. The enzyme from the bacterium Amycolatopsis mediterranei participates in the pathway for rifamycin B biosynthesis. The enzyme also functions as a transaminase earlier in the pathway, producing UDP-α-D-kanosamine [3].
History
created 2013
EC Tree
1.14.11.5 created 1972, deleted 1976
1.14.17.2 created 1972, deleted 1984