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EC 6.3.2.34 Details
EC number
6.3.2.34
Accepted name
coenzyme F420-1:γ-L-glutamate ligase
Reaction
GTP + coenzyme F420-1 + L-glutamate = GDP + phosphate + coenzyme γ-F420-2
Other name(s)
F420:γ-glutamyl ligase, CofE-AF, MJ0768, CofE
Systematic name
L-glutamate:coenzyme F420-1 ligase (GDP-forming)
Comment
This protein catalyses the successive addition of two glutamate residues to cofactor F420 by two distinct and independent reactions. In the first reaction (EC 6.3.2.31, coenzyme F420-0—L-glutamate ligase) the enzyme attaches a glutamate via its α-amine group to F420-0. In the second reaction, which is described here, the enzyme catalyses the addition of a second L-glutamate residue to the γ-carboxyl of the first glutamate.
History
created 2010
EC Tree
1.14.11.5 created 1972, deleted 1976
1.14.17.2 created 1972, deleted 1984