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EC 1.14.14.116 Details
show Brenda entryEC number
1.14.14.116
Accepted name
averantin hydroxylase
Reaction
(1) (1′S)-averantin + [reduced NADPH—hemoprotein reductase] + O2 = (1′S,5′S)-5′-hydroxyaverantin + [oxidized NADPH—hemoprotein reductase] + H2O;;(2) (1′S)-averantin + [reduced NADPH—hemoprotein reductase] + O2 = (1′S,5′R)-5′-hydroxyaverantin + [oxidized NADPH—hemoprotein reductase] + H2O
Other name(s)
AVN hydroxylase,
avnA (gene name),
CYP60A1
Systematic name
(1′S)-averantin,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (5′-hydroxylating)
Comment
A cytochrome P-450 (heme-thiolate) protein isolated from the saprophytic mold Aspergillus parasiticus. Involved in aflatoxin biosynthesis. Does not react with (1′R)-averantin.
History
created 2013 as EC 1.14.13.174, transferred 2018 to EC 1.14.14.116
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.6.5.1 created 1961, deleted 1965 1.14.14.2 created 1972, deleted 1976 1.14.14.4 created 2000, deleted 2002
