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EC 1.14.14.88 Details
show Brenda entryEC number
1.14.14.88
Accepted name
isoflavone 3′-hydroxylase
Reaction
formononetin + [reduced NADPH—hemoprotein reductase] + O2 = calycosin + [oxidized NADPH—hemoprotein reductase] + H2O
Other name(s)
isoflavone 3′-monooxygenase,
CYP81E9
Systematic name
formononetin,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (3′-hydroxylating)
CAS registry number
110183-50-1
Comment
A cytochrome P-450 (heme-thiolate) protein. Also acts on biochanin A and other isoflavones with a 4′-methoxy group. Involved in the biosynthesis of the pterocarpin phytoalexins medicarpin and maackiain.
History
created 1992 as EC 1.14.13.52, transferred 2018 to EC 1.14.14.88
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.6.5.1 created 1961, deleted 1965 1.14.14.2 created 1972, deleted 1976 1.14.14.4 created 2000, deleted 2002
