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EC 1.1.1.405 Details
EC number
1.1.1.405
Accepted name
ribitol-5-phosphate 2-dehydrogenase (NADP+)
Reaction
D-ribitol 5-phosphate + NADP+ = D-ribulose 5-phosphate + NADPH + H+
Other name(s)
acs1 (gene name), bcs1 (gene name), tarJ (gene name), ribulose-5-phosphate reductase, ribulose-5-P reductase, D-ribulose 5-phosphate reductase
Systematic name
D-ribitol-5-phosphate:NADP+ 2-oxidoreductase
Comment
Requires Zn2+. The enzyme, characterized in bacteria, is specific for NADP. It is part of the synthesis pathway of CDP-ribitol. In Haemophilus influenzae it is part of a multifunctional enzyme also catalysing EC 2.7.7.40, D-ribitol-5-phosphate cytidylyltransferase. cf. EC 1.1.1.137, ribitol-5-phosphate 2-dehydrogenase.
History
created 2017
EC Tree
1.6.5.1 created 1961, deleted 1965
1.14.14.2 created 1972, deleted 1976
1.14.14.4 created 2000, deleted 2002