EC Explorer

1.10.3.10

ubiquinol oxidase (H⁺-transporting)

2 ubiquinol + O₂ + n H⁺_{[side 1]} = 2 ubiquinone + 2 H₂O + n H⁺_{[side 2]}

cytochrome bb₃ oxidase, cytochrome bo oxidase, cytochrome bd-II oxidase, ubiquinol:O₂ oxidoreductase (H⁺-transporting)

ubiquinol:oxygen oxidoreductase (H⁺-transporting)

Contains a dinuclear centre comprising two hemes, or heme and copper. This terminal oxidase enzyme generates proton motive force by two mechanisms: (1) transmembrane charge separation resulting from utilizing protons and electrons originating from opposite sides of the membrane to generate water, and (2) active pumping of protons across the membrane. The bioenergetic efficiency (the number of charges driven across the membrane per electron used to reduce oxygen to water) depends on the enzyme; for example, for the bo₃ oxidase it is 2, while for the bd-II oxidase it is 1. cf. EC 1.10.3.14, ubiquinol oxidase (electrogenic, non H⁺-transporting).

created 2011, modified 2014, deleted 2018