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EC 1.3.1.110 Details
EC number
1.3.1.110
Accepted name
lactate dehydrogenase (NAD+,ferredoxin)
Reaction
lactate + 2 NAD+ + 2 reduced ferredoxin [iron-sulfur] cluster = pyruvate + 2 NADH + 2 oxidized ferredoxin [iron-sulfur] cluster
Other name(s)
electron bifurcating LDH/Etf complex
Systematic name
lactate:NAD+,ferredoxin oxidoreductase
Comment
The enzyme, isolated from the bacterium Acetobacterium woodii, uses flavin-based electron confurcation to drive endergonic lactate oxidation with NAD+ as oxidant at the expense of simultaneous exergonic electron flow from reduced ferredoxin to NAD+.
History
created 2015
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