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EC 1.14.15.4 Details
EC number
1.14.15.4
Accepted name
steroid 11β-monooxygenase
Reaction
a steroid + 2 reduced adrenodoxin + O2 + 2 H+ = an 11β-hydroxysteroid + 2 oxidized adrenodoxin + H2O
Other name(s)
steroid 11β-hydroxylase, steroid 11β/18-hydroxylase
Systematic name
steroid,reduced-adrenodoxin:oxygen oxidoreductase (11β-hydroxylating)
CAS registry number
9029-66-7
Comment
A heme-thiolate protein (P-450). Also hydroxylates steroids at the 18-position, and converts 18-hydroxycorticosterone into aldosterone.
History
created 1961 as EC 1.99.1.7, transferred 1965 to EC 1.14.1.6, transferred 1972 to EC 1.14.15.4, modified 1989, modified 2014
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