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EC 1.14.14.137 Details
show Brenda entryEC number
1.14.14.137
Accepted name
(+)-abscisic acid 8′-hydroxylase
Reaction
(+)-abscisate + [reduced NADPH—hemoprotein reductase] + O2 = 8′-hydroxyabscisate + [oxidized NADPH—hemoprotein reductase] + H2O
Other name(s)
(+)-ABA 8′-hydroxylase,
ABA 8′-hydroxylase,
CYP707A1 (gene name)
Systematic name
abscisate,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (8′-hydroxylating)
CAS registry number
153190-37-5
Comment
A cytochrome P-450 (heme-thiolate) protein found in plants. Catalyses the first step in the oxidative degradation of abscisic acid and is considered to be the pivotal enzyme in controlling the rate of degradation of this plant hormone [1]. CO inhibits the reaction, but its effects can be reversed by the presence of blue light [1]. The 8′-hydroxyabscisate formed can be converted into (–)-phaseic acid, most probably spontaneously.
History
created 2005 as EC 1.14.13.93, transferred 2018 EC 1.14.14.137
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.14.15.1 camphor 5-monooxygenase
