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EC 3.13.1.8 Details
show Brenda entryEC number
3.13.1.8
Accepted name
S-adenosyl-L-methionine hydrolase (adenosine-forming)
Reaction
(R)-S-adenosyl-L-methionine + H2O = adenosine + L-methionine
Other name(s)
SAM hydroxide adenosyltransferase
Systematic name
(R)-S-adenosyl-L-methionine hydrolase (adenosine-forming)
Comment
The enzyme, found in bacteria and archaea, is involved in removing the (R) isomer of S-adenosyl-L-methionine from the cell. It catalyses a nucleophilic attack of water at the C5′ carbon of S-adenosyl-L-methionine to generate adenosine and L-methionine.
History
created 2018, deleted 2022
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.14.14.2 created 1972, deleted 1976 1.14.14.4 created 2000, deleted 2002
