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EC 1.3.1.116 Details
show Brenda entryEC number
1.3.1.116
Accepted name
7β-hydroxy-3-oxochol-24-oyl-CoA 4-desaturase
Reaction
7β-hydroxy-3-oxochol-24-oyl-CoA + NAD+ = 7β-hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+
Other name(s)
baiH (gene name)
Systematic name
7β-hydroxy-3-oxochol-24-oyl-CoA Δ4-oxidoreductase
Comment
Contains FAD and FMN. The enzyme, characterized from the bacterium Clostridium scindens, participates in the bile acid 7α-dehydroxylation pathway. The enzyme catalyses the stereo-specific oxidation of its substrate and has no activity with the 7α anomer. cf. EC 1.3.1.115, 3-oxocholoyl-CoA 4-desaturase.
History
created 2018
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.14.14.2 created 1972, deleted 1976 1.14.14.4 created 2000, deleted 2002
