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EC 1.14.12.19 Details
show Brenda entryEC number
1.14.12.19
Accepted name
3-phenylpropanoate dioxygenase
Reaction
(1) 3-phenylpropanoate + NADH + H+ + O2 = 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD+;;(2) (2E)-3-phenylprop-2-enoate + NADH + H+ + O2 = (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + NAD+
Other name(s)
HcaA1A2CD,
Hca dioxygenase,
3-phenylpropionate dioxygenase
Systematic name
3-phenylpropanoate,NADH:oxygen oxidoreductase (2,3-hydroxylating)
Comment
This enzyme catalyses a step in the pathway of phenylpropanoid compounds degradation. It catalyses the insertion of both atoms of molecular oxygen into positions 2 and 3 of the phenyl ring of 3-phenylpropanoate or (2E)-3-phenylprop-2-enoate.
History
created 2005, modified 2011
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.14.13.45 created 1992, deleted 2003
