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EC Explorer

EC 3.6.4.13 Details
EC number
3.6.4.13
Accepted name
RNA helicase
Reaction
ATP + H2O = ADP + phosphate
Other name(s)
CSFV NS3 helicase, DBP2, DbpA, DDX17, DDX25, DDX3, DDX3X, DDX3Y, DDX4, DDX5, DEAD-box protein DED1, DEAD-box RNA helicase, DEAH-box protein 2, DEAH-box RNA helicase, DED1, Dex(H/D) RNA helicase, EhDEAD1, EhDEAD1 RNA helicase, eIF4A helicase, KOKV helicase, Mtr4p, nonstructural protein 3 helicase, NPH-II, RHA, RNA helicase A, RNA helicase DDX3, RNA helicase Hera, RNA-dependent ATPase, TGBp1 NTPase/helicase domain, VRH1, GRTH/DDX25
Systematic name
ATP phosphohydrolase (RNA helix unwinding)
Comment
RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. Some of them unwind RNA with a 3′ to 5′ polarity [3], other show 5′ to 3′ polarity [8]. Some helicases unwind DNA as well as RNA [7,8]. May be identical with EC 3.6.4.12 (DNA helicase).
History
created 2009
EC Tree
1.1.5.1 created 1983, deleted 2002