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EC 3.6.1.54 Details
show Brenda entryEC number
3.6.1.54
Accepted name
UDP-2,3-diacylglucosamine diphosphatase
Reaction
a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-α-D-glucosamine + H2O = a lipid X + UMP
Other name(s)
lpxH (gene name),
UDP-2,3-diacylglucosamine hydrolase,
UDP-2,3-diacylglucosamine pyrophosphatase,
ybbF (gene name),
UDP-2,3-bis[(3R)-3-hydroxymyristoyl]-α-D-glucosamine 2,3-bis[(3R)-3-hydroxymyristoyl]-β-D-glucosaminyl 1-phosphate phosphohydrolase (incorrect),
UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosamine 2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosaminyl 1-phosphate phosphohydrolase
Systematic name
UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-α-D-glucosamine 2-N,3-O-bis[(3R)-3-hydroxyacyl]-α-D-glucosamine-1-phosphate phosphohydrolase
Comment
The enzyme catalyses a step in the biosynthesis of lipid A.
History
created 2010, modified 2021
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1 Oxidoreductases
1.1.1 With NAD+ or NADP+ as acceptor
1.1.99.15 created 1978, deleted 1980 1.1.99.17 created 1982, deleted 2003 1.5.99.7 created 1976, deleted 2002 1.5.99.10 created 1999, deleted 2002
