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EC 4.1.2.45 Details
EC number
4.1.2.45
Accepted name
trans-o-hydroxybenzylidenepyruvate hydratase-aldolase
Reaction
(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H2O = salicylaldehyde + pyruvate
Other name(s)
2′-hydroxybenzalpyruvate aldolase,
NsaE,
tHBPA hydratase-aldolase
Systematic name
(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate hydro-lyase
Comment
This enzyme is involved in naphthalene degradation. The enzyme catalyses a retro-aldol reaction in vitro, and it accepts a broad range of aldehydes and 4-substituted 2-oxobut-3-enoates as substrates [4].
History
created 2010, modified 2011
EC Tree
1.1.99.15 created 1978, deleted 1980
1.1.99.17 created 1982, deleted 2003