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EC 2.1.1.161 Details
show Brenda entryEC number
2.1.1.161
Accepted name
dimethylglycine N-methyltransferase
Reaction
S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine
Other name(s)
BsmB,
DMT
Systematic name
S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase (betaine-forming)
Comment
This enzyme, from the marine cyanobacterium Synechococcus sp. WH8102, differs from EC 2.1.1.157, sarcosine/dimethylglycine N-methyltransferase in that it cannot use sarcosine as an alternative substrate [1]. Betaine is a ’compatible solute’ that enables cyanobacteria to cope with osmotic stress by maintaining a positive cellular turgor.
History
created 2007
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1 Oxidoreductases
1.1.1 With NAD+ or NADP+ as acceptor
1.1.99.15 created 1978, deleted 1980 1.1.99.17 created 1982, deleted 2003
