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EC 1.1.99.6 Details
EC number
1.1.99.6
Accepted name
D-lactate dehydrogenase (acceptor)
Reaction
(R)-lactate + acceptor = pyruvate + reduced acceptor
Other name(s)
D-2-hydroxy acid dehydrogenase, D-2-hydroxy-acid dehydrogenase, (R)-2-hydroxy-acid:acceptor 2-oxidoreductase
Systematic name
(R)-lactate:acceptor 2-oxidoreductase
CAS registry number
9028-83-5
Comment
The zinc flavoprotein (FAD) from the archaeon Archaeoglobus fulgidus cannot utilize NAD+, cytochrome c, methylene blue or dimethylnaphthoquinone as acceptors. In vitro it is active with artificial electron acceptors such as 2,6-dichlorophenolindophenol, but the physiological acceptor is not yet known.
History
created 1965, modified 2013
EC Tree
1.1.99.15 created 1978, deleted 1980
1.1.99.17 created 1982, deleted 2003